The Anti-Spiral (Gurren Lagann) decide that they want to conquer all of fiction so they recruit Dr. Doom (Marvel), Thanos, and Lex Luthor (DC). They will be traveling to different universes and stealing the most valuable items from them. They spend a year on prep.
They go to the DC universe to convince Lucifer Morningstar to join them. He says he’ll ally with them if they can steal the Ultimate Nullifier. If they fail to steal it, he’ll join the other team. They continue traveling around brainwashing heroes and recruiting allies from different verses. They took over Warhammer 40,000 Imperium and the annihilation wave. Next they traveled to the Skullduggery Pleasant Universe to resurrect and brainwash Argeddion, and retrieve Darquesse from the dimension she resides in. They’ve also reverse engineered the Accelerator and boosted it with Spiral power. They use the Accelerator on Darquesse and Argeddion to boost their magical power x300. Doom uses it on himself as well. They even take people from Marvel, DC, and Image and turn them to mind slaves.
Meanwhile, Franklin Richards becomes aware of what the villains are planning after Thor goes missing, so he warns Tony and Reed about what’s happening. And thus they set out on their quest to find allies. In Hyperion verse they found Shrike (Hyperion Cantos), Lord of Pain and master of speed. In Bastard verse they found Dark Schneider. They got the Forerunners in Halo. In DC they found Anti-Monitor (pre-new 52, Sinestro Wars version), Wonder Woman, Martian Manhunter, John Stewart, and had no choice but to hire Darkseid (who was quite angry that team villain didn’t call him, so he would’ve joined anyway), who in turn brings Despero with him. Once Onslaught (Xavier & Magneto) heard about this event he also decided to join and he even brought Adam Warlock. Reed also hired Brainiac and Mr. Majestic.
Team Villain sends a squad back to Marvel in order to take the Nullifier and secure Lucifer’s help. The Nullifier is being kept in a S.H.I.E.L.D Base in the Himalayas guarded by agents as well as Captain Marvel and John Stewart.
Team Villain’s bloodlusted Nullifier retrieval unit:
Peak Spawn (pre-god)
616 Sorcerer Supreme Dr. Strange
Team Reed has sent the following to intercept them:
Onslaught (Xavier & Magneto)
They start in Death Valley.